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Cervical Cell Changes on a Pap Test

Table of Contents


Overview

Cervical cell changes are classified according to their degree of abnormality using the Bethesda system (TBS). Further evaluation decisions are guided by the kinds of changes seen in the cells.

Minor cell changes

Minor cell changes may go away without treatment. But sometimes they turn into more serious cell changes. Types of minor cell changes include:

Moderate to severe cell changes

Moderate to severe cervical cell changes (also called moderate to severe dysplasia) mean cell changes that are more likely to be precancerous and develop into cervical cancer if left untreated. Moderate to severe cervical cell changes are classified in the Bethesda system (TBS) as high-grade squamous intraepithelial lesions (HSIL) or atypical glandular cells (AGC). Follow-up evaluation is needed, and treatment may be needed.

All abnormal Pap tests require follow-up to identify development of more severe cell changes, including cervical cancer. Most abnormal cells can be removed or destroyed before they become cancerous.


Credits for Cervical Cell Changes on a Pap Test

Current as of: November 27, 2023

Author: Healthwise Staff (https://www.healthwise.org/specialpages/legal/abouthw/en)
Clinical Review Board (https://www.healthwise.org/specialpages/legal/abouthw/en)
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