General Medicine Instructions after Transplant

General Medicine Instructions after Transplant


After transplant, you will be taking many medicines. Take your medicines as ordered by your transplant and primary care doctors.


Anti-rejection medicines

You will take anti-rejection medicines for the rest of your life. Your transplant doctors will adjust the doses of your transplant medicines based on the results of your lab values and vital signs.

  • Do not miss any doses of your medicines.
  • If you do miss a dose, you will need to carefully consider retiming that day's doses.
    • Take the missed dose when you remember, if it is less than 5 hours past the scheduled time. Then retime your medicines so they are spaced throughout the rest of the day. Call your transplant coordinator if you have questions.
    • Skip the missed dose if it is more than 5 hours past the scheduled time and then go back to your regular schedule.
    • Do not ever take an extra dose of your anti-rejection medicine in an attempt to "catch up".

If you are not able to take your medicine because of nausea, retry in an hour or two.

  • Try clear liquids and the BRAT diet (bananas, rice, applesauce and dry toast) to see if the nausea goes away.
  • If you are not able to take your medicine or you are not able to keep it down after 2 to 3 hours, call your coordinator.

After your transplant, your nurse will set up a self-administered medicine program for you in the hospital. This program will help you learn about your medicines - what they look like, what they are used for, when you take each medicine and about their side effects. You will be expected to take your medicines as if you were at home.



Avoid grapefruit and pomegranates as these fruits affect how some transplant medicines are absorbed in the body. Read blended juice labels to check for these ingredients. 

Do not take herbal products after your transplant. Herbal products are sold as food supplements, and they are not checked like other medicines. Information on their safety, side effects or drug interactions are not always known. Taking herbs can interact with your transplant medicines. 

Talk to your transplant doctor, pharmacist or transplant coordinator if you have any questions about the medicines you take.


Working with your primary care doctor

After transplant, you need to keep both your primary care and transplant doctor as health partners. They need to work closely with each other to adjust your other medicines.

Tell your transplant coordinator right away if your primary care doctor:

  • Changes any doses of your other medicines.
  • Starts you on a new medicine.
  • Stops a current medicine.

This is done to keep your medicine record up to date.

Call your coordinator if you have questions about over the counter medicines. 


© 2000 – August 29, 2019, The Ohio State University Wexner Medical Center.

This handout is for informational purposes only. Talk with your doctor or healthcare team if you have any questions about your care. For more health information, call the Library for Health Information at 614-293-3707 or email: