Capsaicin(Zostrix), available without a prescription, is a pain reliever that comes in a cream that you apply directly to your skin (topical analgesic). It has been found to relieve joint pain from osteoarthritisin some people when rubbed into the skin over affected joints. 1To be beneficial, the cream must be applied 3 or 4 times a day. And the effects may not be seen for several weeks.
The main ingredient in capsaicin is an extract from hot peppers. It appears to have no serious side effects. But some people may be allergic to capsaicin. The first time you use this topical cream, apply it to just a small area of skin to make sure there is no allergic reaction. Even people who are not allergic may notice a burning sensation. Some people may not be able to tolerate the discomfort associated with using capsaicin.
- De Silva V, et al. (2011). Evidence for the efficacy of complimentary and alternative medicines in the management of osteoarthritis: A systematic review. Rheumatology, 50(5): 911–920.
Current as of: April 30, 2021
Author: Healthwise Staff
Medical Review: Anne C. Poinier MD - Internal Medicine
Martin J. Gabica MD - Family Medicine
Kathleen Romito MD - Family Medicine
Stanford M. Shoor MD - Rheumatology