Trimipramine Oral Capsule (TRIMIPRAMINE - ORAL)

For depression.

Generic Name: Trimipramine

Instructions

This medicine may be taken with or without food.

Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.

To relieve dry mouth, chew gum, suck on hard candy/ice chips, drink extra water, or use a saliva substitute.

This medicine will work best if you take it at about the same time every day.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

Drink plenty of water while on this medicine.

To reduce constipation, eat high fiber foods, drink plenty of water and exercise.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.

It may take several weeks for this medicine to fully work.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

If you need to stop this medicine, your doctor may wish to gradually reduce the dosage before stopping.

This medicine may affect your blood sugar levels. If you have diabetes, talk to your doctor before changing the dose of your diabetes medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting, especially after exercising or in hot weather. Be very careful when standing or sitting up quickly.

If possible, avoid using with alcohol, marijuana, or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Avoid becoming overheated during exercise or other activities. Try to stay cool in hot weather.

Family should check on the patient often. Call the doctor if patient becomes more depressed, has thoughts of suicide, or shows changes in behavior.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Some patients have serious side effects from this medicine. Ask your pharmacist to show you the information from the Food and Drug Administration (FDA) and discuss it with you.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • change in appetite
  • blurry vision
  • constipation
  • dizziness or drowsiness
  • headaches
  • difficulty or discomfort urinating
  • weakness
  • change in weight

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • decreased awareness or responsiveness
  • loss of balance
  • change in behavior
  • bleeding or bruising
  • chest or jaw pain
  • changes in memory, mood, or thinking
  • confusion
  • severe or persistent constipation
  • cough that does not go away
  • swelling of the legs, feet, and hands
  • pain in the eye
  • fainting
  • feeling cold or numb, especially in arms and legs
  • high fever
  • hallucinations (unusual thoughts, seeing or hearing things that are not real)
  • severe or persistent headache
  • fast, irregular, or slow heartbeat
  • seeing flashes or halos around lights
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • muscle aches, spasms or abnormal movements
  • nervousness
  • restlessness
  • ringing in the ears
  • seizures
  • problems with sexual functions or desire
  • shakiness
  • red, peeling or blistering skin
  • difficulty speaking
  • symptoms of stroke (such as one-sided weakness, slurred speech, confusion)
  • suicidal thoughts
  • severe or persistent vomiting

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.